During the event Unreconciled Stars, while Pierro does not make a personal appearance, he was responsible for sending Scaramouche to Liyue. While investigating the meteor at Musk Reef, Scaramouche makes a discovery: "The stars, the sky... It's all a gigantic hoax. A lie." Believing that Pierro had foreseen the meteorite showers and the discovery he would make, Scaramouche leaves in an irritable mood, presumably to confront the senior Harbinger.

Pierro masterminded the Fatui's involvement in Inazuma. To prolong the war, create a demand for Delusions, and secure their supply of materials to create more Delusions, Pierro sent Nathan to infiltrate the Watatsumi Army, sabotage their efforts, and create chaos on Yashiori Island. Scaramouche was also dispatched to oversee the Delusion Factory's operations, while Signora manipulated the Kanjou Commission and otherwise continued her mission of collecting the Gnoses. After the Fatui's actions were exposed, Pierro had an order sent to Borenka to withdraw from Yashiori Island and bring back the few Shogunate renegades to him as test subjects for an unknown experiment.